Experiment_9 - Experiment 9: Synthesis of Benzoic Acid via...

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Synthesis of Benzoic Acid via Carbonylation of a Grignard Reagent Organometallic compounds such as Grignard reagents are versatile intermediates in the synthesis of alcohols, carboxylic acids, alkanes and ketones. The synthesis of a Grignard reagent requires the reaction of an alkyl or aryl halide with magnesium metal. In this experiment, you will be reacting bromobenzene with magnesium to yield phenylmagnesium bromide. Often Grignard reagents are prepared under inert atmospheres such as nitrogen to prevent its reaction with oxygen and water. The preparation that you will be doing does not use rigorously anhydrous conditions but the phenylmagnesium bromide will be nonetheless protected from oxygen by a blanket of refluxing ether. Mg Br MgBr dry ether bromobenzene phenylmagnesium bromide Reaction of the Grignard reagent, phenylmagnesium bromide with carbon dioxide gives benzoic acid after acid hydrolysis. MgBr
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This note was uploaded on 11/14/2010 for the course CHEM CHEM266L taught by Professor Christine during the Fall '10 term at Waterloo.

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Experiment_9 - Experiment 9: Synthesis of Benzoic Acid via...

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