Bis2CFall10.Lecture13

Bis2CFall10.Lecture13 - Lecture 13: BIS 002C BIODIVERSITY...

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Lecture 13: BIS 002C BIODIVERSITY AND THE TREE OF LIFE Lecture 13: Human Associated Microbes 1 Saturday, October 16, 2010
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Where we are going and where we have been • Previous lecture : ! 12. Extremophiles and studying microbes • Current Lecture: ! 13. Human associated microbes • Next Lecture: ! Midterm #1 2 Saturday, October 16, 2010
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Outline Lecture 13 • Symbioses • Human associated microbes and the uses of phylogeny ! Anthrax ! Flu ! The human microbiome 3 Saturday, October 16, 2010
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A. Midterm 4 A. Midterm Saturday, October 16, 2010
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Midterm Review Sessions 5 Midterm Review Sessions SciLec 123 11 AM -12 Noon Saturday and Sunday No planned topics Bring specific questions that you would like me to review Saturday, October 16, 2010
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Room Assignments • Section A 6:10-7:00 PM ! A-G 176 Everson ! H-Ka 234 Wellman ! Ke-Z 194 Chemistry • Section B 7:10-8:00 PM ! A-E 106 Wellman ! F-Z 194 Chemistry 6 Saturday, October 16, 2010
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B. Symbioses 7 B. Introduction to symbioses Saturday, October 16, 2010
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Symbioses Symbiosis is an intimate association between at least two different organisms in which at least one of them benefits 8 Saturday, October 16, 2010
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Symbioses Symbiosis is an intimate association between at least two different organisms in which at least one of them benefits • Today: Two aspects of symbioses. ! Human associated microbes ! Applied phylogenetic analysis 9 Saturday, October 16, 2010
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Classes of symbiosis Orga nism Class of symbiosis A B Mutualism + + Commensalism + 0 Parasitism + - 10 Saturday, October 16, 2010
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II. Some terms Pathogens are infectious agents that cause a disease (can be considered a subclass of parasites) Pathogenicity = ability to enter a host and cause disease Virulence = degree of pathogenicity • Note - not all parasites are pathogens but all pathogens are parasites 11 Saturday, October 16, 2010
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No archaeal pathogens • Lots of types of pathogens ! Bacteria that infect eukaryotes ! Viruses that infect eukaryotes, archaea and bacteria ! Eukaryotes that infect other eukaryotes • No known archaeal pathogens of any organism ! No clear explanation of why ! If you discover one, you will become famous (well, among scientists) 12 Saturday, October 16, 2010
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C. Example 1: Anthrax Letters 13 Anthrax Saturday, October 16, 2010
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Classes of symbiosis Orga nism Class of symbiosis A B Mutualism + + Commensalism + 0 Parasitism + - 14 Saturday, October 16, 2010
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