Bio2051ch6

Bio2051ch6 -...

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Chapter 6- Virus Structure and Function *Highly recommended that you read this chapter General Properties of Viruses (virions) ____obligate intracellular parasite (virus must be inside a host cell)____      made of nucleic  acid surrounded by a protein coat. Only replicate inside a host No nucleus, organelles, cytoplasm Viral genomes contain information for taking over host cell information for making viral proteins Capsid, genome replication proteins Virus Structure—Capsids Capsid- protein coat surrounding nucleic acid Capsid Proteins are arranged to give virion symmetry  __Icosahedral__      capsids Roughly spherical 20 equilateral triangles  Many animals __Filamentous     __ capsids  Long _tube of protein _, with genome inside Tube made up of 100’s of identical protein subunits Tube length reflects size of viral genome __Complex__      capsids 
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Many bacteriophage (viruses that infect bacteria) _Asymmetrical _ shapes Tend to be larger viruses  Poxviruses *Study Bacteriophage in book Virus Structure—Envelopes Envelope- lipid bilayer around capsid of some viruses Allows __fusion to host cell__  or organelle membrane Only occurs if host cell not covered by __cell wall__ __bacteriophages     __ are NON-enveloped Envelope lipids come from __host_ Not encoded by viral genome __proteins embedded in envelope__      may be encoded by virus Coats viral capsid as virus leaves cell or organelle Virus Structure—Genome DNA or RNA Single (ss) or double-stranded (ds) Linear or circular Includes genes encoding viral proteins Capsid Envelope Proteins if virus is enveloped Any polymerase not found in host cell
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Bacteriophage Life Cycles 1. Attachment to host cell receptor proteins Bacterial cell receptors normally used for bacterial purposes Examples: sugar uptake, iron uptake, conjugation Virus takes advantage of host proteins 2. Injects genome through cell wall to cytoplasm
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Bio2051ch6 -...

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