Hrincevich+CH+12+ADDITIONAL+MATERIAL+student+outline

Hrincevich+CH+12+ADDITIONAL+MATERIAL+student+outline -...

Info iconThis preview shows pages 1–20. Sign up to view the full content.

View Full Document Right Arrow Icon
Chromosomes and Human Genetics Chapter 12 (Additional Topics: no additional readings, but focus on THIS lecture material for exam questions)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Chromosomes & Cancer
Background image of page 2
Philadelphia Chromosome
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Re-examining Mendel’s Work
Background image of page 4
Homologous Chromosomes
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Alleles 0
Background image of page 6
a b c a b c A B C A B C A B C a b c a b c b c A A B C B C a 0 How Crossing Over Creates New Allele Combinations in Gametes These segregate into separate gametes
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Sex Chromosomes Discovered in late 1800s Mammals, fruit flies XX is female, XY is male In other groups XX is male, XY female Human X and Y chromosomes function as homologues during meiosis 0
Background image of page 8
Karyotype Preparation - Stopping the Cycle Cultured cells are arrested at metaphase by adding colchicine This is when chromosomes are most condensed and the easiest to identify 0
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Karyotype Preparation Arrested cells are broken open Metaphase chromosomes are fixed and stained Chromosomes are photographed through microscope Photograph of chromosomes is cut up and arranged to form karyotype diagram 0
Background image of page 10
0
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
0 Karyotype.swf (use Apple Quicktime to open and view)
Background image of page 12
Sex Determination X X Y X XX XY XX XY X X Y X x x eggs sperm female (XX) male (XY) 0
Background image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
0 Sex Determination.swf (use Apple Quicktime to open and view)
Background image of page 14
The Y Chromosome Fewer than two dozen genes identified on the Y One is the master gene for male sex determination SRY gene (sex-determining region of Y) SRY present, testes form SRY absent, ovaries form 0
Background image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Effect of Y Chromosome 10 weeks Y present Y absent 7 weeks birth approaching appearance of structures that will give rise to external genitalia appearance of “uncommitted” duct system of embryo at 7 weeks Y present Y absent testis ovary testes ovaries 0
Background image of page 16
The X Chromosome Carries more than 2,300 genes Most genes deal with non-sexual traits Genes on X chromosome can be expressed in both males and females 0
Background image of page 17

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
0 X X X Y x Gametes: 0 Discovering Linkage homozygous dominant female recessive male Gametes: X X X Y x 1/4 1/4 1/4 1/4 1/2 1/2 1/2 1/2 F 2 generation: 1/4 All F 1 have red eyes male female
Background image of page 18
Linkage Groups “Linked genes” on a chromosome are closely located to each other Linked genes tend to be transmitted together Linkage can be disrupted by crossing-over events Thomas Morgan researched this area Fruit flies 4 homologous chromosomes 4 linkage groups Not all genes on chromosomes are tightly linked Complete vs. Incomplete linkage 0
Background image of page 19

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 20
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/18/2010 for the course BIOL 1001 taught by Professor Minor during the Spring '08 term at LSU.

Page1 / 67

Hrincevich+CH+12+ADDITIONAL+MATERIAL+student+outline -...

This preview shows document pages 1 - 20. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online