Exam1-2009Key - KEY_ Name (Last, First) BIO 361 _ SOLAR ID...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
KEY _______________________________ _____________________________________ Name (Last, First) SOLAR ID 1 BIO 361 EXAM 1 FALL 2009 Version A NAME:___________KEY _________________________________ ID:_____________________________________________________ 1. Write Your name and ID on all pages 2. Write all answers in pen only 3. Make sure your exam has six pages including this cover page Page 2 _______________ Page 3 _______________ Page 4 _______________ Page 5 _______________ Page 6 _______________ Total _______________ (93 total points) (All True/False = 3 points; multiple choice = 4 points; Sequencing question = 10 points (partial credit for this question only)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
KEY _______________________________ _____________________________________ Name (Last, First) SOLAR ID 2 I. You have been given two protein samples, X and Y, in aqueous solution. Both proteins are in their native state at 37°C. Which of the following statements are true and which are false? (Write T or F clearly) 1. __T___ Based on thermodynamic considerations alone, both proteins will eventually fall apart, but this event is not likely to occur within a finite time period. 2. __F___ If protein Y unfolds from its native conformation as the temperature is raised, this information would be sufficient to rule out the possibility that unfolding is associated with an increase in enthalpy. 3. __F___ If the native conformation of protein Y has an interior with abundant leucine and valine side chains, you would expect that the entropy of the solution of Y (protein + solvent) would be greater when the protein was unfolded, regardless of temperature. 4. __T___ It is possible that when the temperature of the solution of protein X is lowered from 37° to 4°, the protein will unfold spontaneously, because the effect of entropy loss in the solution on the change in free energy upon protein unfolding is reduced at lower temperatures while effect of the enthalpy loss on the change in free energy upon protein unfolding is temperature independent. 5. __F___ It is possible that when protein X is dissolved in aqueous buffer at 37°, there will be a marked increase in the fraction of water molecules assembled into clatherates, thereby stabilizing the protein. II. You have been given one millimole each of a series of samples which contain either an amino acid or a peptide. Which of the following statements are true and which are false? (Write T or F clearly) 6. __F___ If the only naturally occurring amino acid found in sample A is alanine after amino acid analysis of an acid hydrolyzate of the sample, you would expect that two millimoles of base would be taken up after complete titration of the original sample from a starting pH of below 2 to pH 14, regardless of whether the sample had first been subjected to acid hydrolysis before titration. 7. __T___ If you discovered that two millimoles of base were consumed when you titrated sample B from
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 6

Exam1-2009Key - KEY_ Name (Last, First) BIO 361 _ SOLAR ID...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online