Lec2010-FA-breakdown-I

Lec2010-FA-breakdown-I - 1 Fatty Acid Breakdown I Lecture...

Info iconThis preview shows pages 1–9. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Fatty Acid Breakdown I Lecture 20 Chapter 20-1 Office hours: 11 am to 12:00 pm Monday, Wednesday & Friday CMM Room 142 Phone: 632-1401 Huilin.Li@StonyBrook.edu
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 Mammal hybernation Bird migration Camel crossing desert
Background image of page 2
Fatty Acids: Long alkyl chains with carboxylic acid at one end (head). General forumula: CH 3 -(CH 2 ) n -COO - (number from carboxylate) Stearic acid: saturated C18 18:0 Oleic acid: unsaturated C18 18:1 Δ 9 (all natural double bonds are cis!) Linoleic acid: C18, two unsaturations 18:2 Δ 9 Δ 12 Linolenic acid: C18, three unsaturations 18:3 Δ 9 Δ 12 Δ 15 α β γ ω Alternative numbering
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4 Fatty acid is one type of lipid choline
Background image of page 4
5 Cis and Trans Fatty Acids all natural double bonds are cis!
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6 Table 9-1 1. ~ 40 different fatty acids occur naturally 2. Fatty acids contain an even number of C atoms, typically 12 - 20 atoms. 3. Saturated fatty acids have much higher melting point than unsaturated Human T = 37 °C
Background image of page 6
7 Saturated fats have higher melting points than unsaturated fats. This can be explained in terms of differences in the packing of the molecules in the solid state. The long hydrocarbon chains in saturated fat molecules can be packed quite closely together which maximizes the van der Waals forces. Unsaturated fats (oils) contain one or more double bond in cis configuration. This introduces a 'kink' into the hydrocarbon chain since there is restricted rotation around this bond. This makes close packing much more difficult The intermolecular forces are weaker and so Unsaturated fats have lower melting points than saturated fats. ! Δ G= Δ H-TS
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
8 Functions of Fatty Acids in Mammals Membrane components: Building blocks for phospholipids, glycolipids. Fuel molecules for energy storage Post-translational modification of proteins. – Causes protein to associate with membranes. Serve as hormones and second messengers – Prostaglandins are derived from Arachidonic acid prosta(te) + gland + -in - because it was originally believed to be secreted from the prostate). -
Background image of page 8
Image of page 9
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 11/19/2010 for the course BIO 361 taught by Professor Lake during the Fall '08 term at SUNY Stony Brook.

Page1 / 40

Lec2010-FA-breakdown-I - 1 Fatty Acid Breakdown I Lecture...

This preview shows document pages 1 - 9. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online