Lecture19-2010 - Lecture 19 BIO361 EXAM 2 MONDAY OCTOBER 25...

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Lecture 19, BIO361 1 EXAM 2: MONDAY, OCTOBER 25, 8:30-10 PM Javits 100 Covers lectures 10-19 Approximately 10 points/lecture: – 80 points from Dr. Simon’s lectures. – 20 points from Dr. Haltiwanger’s lectures. In class review session: Friday, Oct. 22. TA review: Wednesday, Oct. 20, 6:50-8:10 pm, Javits 100. Introduction to Metabolism Chapter 13 Figure 14-2 Metabolism consists of two major sets of competing pathways: Catabolic Anabolic (Protein, Lipids, Carbohydrates) (CO 2 + H 2 O) (e - ) Figure 14-4 Adenosine Triphosphate (ATP): The energy currency of the cell
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Lecture 19, BIO361 2 Our bodies turnover an enormous amount of ATP each day Total ATP in adults: ~100 g Consumption of ATP under: – Resting conditions: 40 kg/day – Running: 30 kg/hour Metabolic pathways: A -------> B -------> C -------> D -------> E -------> F -------> G Metabolites or Intermediates How do we do this? Enzymes 1 2 3 4 5 6 Chapter 14 Opener Table 11-2
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Lecture 19, BIO361 3 Box 14-1 Figure 14-3 Overview of Catabolism Question we want to answer this fall: How does a cell extract energy from it’s environment and convert it to ATP? (e - ) Box 14-1 table What makes a good fuel? Highly reduced. Soluble in water. Fatty acids Carbohydrates Oxidation: loss of e - Reduction: gain of e - (Most reduced) (least reduced) Table 14-3 Metabolic pathways are compartmentalized:
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