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TA Exam III Review2010

TA Exam III Review2010 - Exam I I I Review Dan Roo and...

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Unformatted text preview: Exam I I I Review Dan Roo and Tahir Ahmad Lectures 20-22 i. Fatty Acid Breakdown I ii. Fatty Acid Breakdown I I iii. Fatty Acid Biosynthesis Some I mportant Questions on Fatty Acids I . Why do unsaturated fatty acids have lower melting point? • Presence of double bonds that introduces kink • The kink will prevent closer and tighter packing of the molecule • Hence, molecular interaction with each other will be weakened causing U/S fatty acids to have lower melting point than saturated fatty acid I I . Why do fatty acids usually have even number of carbons? • Problem with the product generated: I f the chain was even, then you get more acetyl-CoA relative to odd chains. • Only product from even number chains is acetyl-CoA, which serves multiple purposes in the cell. • Odd number chains create proprionyl-CoA, which cannot enter β-oxidation. • Proprionyl-CoA must be metabolized by other mean. I t is converted to succinyl-CoA, which could be used as an intermediate to drive CAC forward. •...
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TA Exam III Review2010 - Exam I I I Review Dan Roo and...

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