Bio Lecture 9 Proteins and Nucleic Acids

Bio Lecture 9 Proteins and Nucleic Acids - Lecture 9:...

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Unformatted text preview: Lecture 9: Proteins and Nucleic Acids Wednesday 10/14/09 Reading Chapter 5 pgs. 77-89 Proteins Function support, storage, transport, signaling, receptors, movement, catalysis, defense Structure Amino Acids: monomers, combine to form polymers Polypeptide: polymer of AAs in specific sequence Protein: one or more polypeptides with specific 3- D conformation Amino acids polypeptides proteins Amino Acids Structure Alpha Carbon Amino group Hydrogen Carboxyl group R group: variable side chain Hydrophobic (9/20) Hydrophilic (polar 6/20) Ionized (acids and bases) (5/20) Formation of polypeptides AA are joined by dehydration reactions. peptide bond (covalent) Polypeptide Amino end N terminus Carboxy end C terminus Few to thousands of monomers (aa) The function of a protein depends on its conformation There are three levels of structure in a single polypeptide that organize the folding Primary Secondary Tertiary Two or more polypeptides (oligomer) Quaternary structure Primary structure Determined by AA sequence To perform its function, it must fold properly!...
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This note was uploaded on 11/19/2010 for the course BIOLOGY 93 taught by Professor O during the Spring '08 term at San Diego.

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Bio Lecture 9 Proteins and Nucleic Acids - Lecture 9:...

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