Lecture 19 Molecular Biology

Lecture 19 Molecular Biology - Unit VI Molecular Biology...

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Unit VI: Molecular Biology Lecture 19: DNA--The molecular basis of heredity Lecture 20: From genotype to phenotype Lecture 21: Chromatin organization and regulation of gene expression Lecture 22: Introduction to recombinant DNA technology
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Reading: Chapter 16, pages 305-314 Bio 93 Fall 2008 Lecture 19 DNA - The Molecular Basis of Heredity Monday 11/9/09
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Keep history in mind…. 1850s--Mendel--”hereditary factors” 1875-1890s--Meiosis and Mitosis worked out via microscopy and cytology 1902--chromosome theory of inheritance 1930s--Morgan shows genes are located on chromosomes
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What experiments convinced most biologists that DNA is the genetic material? -Experiments in which bacteria were infected with a virus Dna is the genetic material DNA structure is a double helix with hydrogen bound base pairs as the rungs of the ladder DNA serves as the template for its own replication
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Living S cells (control) Living R cells (control) Heat-killed S cells (control) Mixture of heat-killed S cells and living R cells Mouse dies Mouse dies Mouse healthy Mouse healthy Living S cells RESULTS EXPERIMENT
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How do heat-killed smooth bacteria (S. pneumoniae) get rough bacteria to be pathogenic? - heritable material was transferred from smooth to rough bacteria that allowed the R (rough) cells to make capsules
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In 1952, Alfred Hershey and Martha Chase showed that DNA was the genetic material of the phage T2. The T2 phage, consisting almost
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This note was uploaded on 11/19/2010 for the course BIOLOGY 93 taught by Professor O during the Spring '08 term at San Diego.

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Lecture 19 Molecular Biology - Unit VI Molecular Biology...

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