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Unformatted text preview: Assignment #1
Think about what you have learned about molecular structure not just from a purely scientific perspective, but from a conceptual perspective. What concepts and associated relationships would you need to capture to create a database or data structure to retrieve data on a ny biomolecular structure (e.g. protein, DNA, RNA, peptide, carbohydrate, lipid, drug)? An important aspect of systems biology is the ability to place singular concepts in the broader functional context of a system. What concepts (attributes) and relationships would you need to completely represent the interactions among these molecules (e.g. protein-protein, protein-DNA, protein-RNA, enzyme-metabolite, receptor-peptide, protein-drug)? In bioinformatics, it is also very important to be aware of the existing data sources available. There is a wealth of valuable public data available in the broadly used databases (e.g. PDB, GenBank, KEGG) as well as more sub-field-specific databases (e.g. BioPD, HMDB, DrugBank, DIP). Research the existing public data sources that are relevant for the concepts and relationships you’ve come up with. 11/21/10 Pharm201 Assignment 11 Assignment #1- Example
Secondary Structure _type _ attributes is_part_of is_part_of Helix _type _attributes RNA _type _attributes DNA _type _attributes is_part_of Points will be awarded for the number of concepts (boxes) you include and the number of attributes associated with each concept 11/21/10 Pharm201 Assignment 22 ...
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This note was uploaded on 11/20/2010 for the course PHAR 201 taught by Professor Bourne,p during the Spring '08 term at UCSD.
- Spring '08