Week3Handout - Name __________________________ Insulin mRNA...

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Week 3 Worksheet Part 1 Which cellular structures or organelles are shown below? Complete the table on the next page. Name __________________________ A B C D F G H (hint: low pH) I J K L E
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Name Function A B C D E F G H I J K L Name __________________________
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Part 2 Insulin is a hormone that is vital for glucose metabolism. It is synthesized by specialized cells in the pancreas, called beta cells, and secreted into the bloodstream. Insulin triggers glucose uptake in muscle, liver, and fat cells where it is then broken down to generate energy or stored for later use as glycogen. The INS gene encodes for insulin. To produce insulin, beta cells must Frst transcribe the DNA sequence contained in the INS gene to produce a mRNA transcript. A. How does this mRNA transcript exit the nucleus? B. Starting at the point the mRNA forms a complex with a ribosome, map out the path Insulin will take from its synthesis to when it is secreted by the cell.
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Unformatted text preview: Name __________________________ Insulin mRNA exits the nucleus mRNA forms a complex with a ribosome and translation (protein synthesis) begins while in the cytosol C. Which fgure shows the means by which insulin is able to signal to its target cells in muscle, liver, and Fat tissue? How would you explain this mean oF cellular communication to someone who is not a bio major? 1 2 3 D. What are the diFFerences between the 3 means oF cell-cell communication shown above? E. Insulin s receptor on its target cells is a member oF the receptor tyrosine kinase Family. How does this type oF receptor diFFer From a G protein-coupled and ion channel receptors? Part 3 or the 3 molecules below, describe the bonds between the atoms and how this aFFects their ability to cross the plasma membrane. CO 2 H 2 O NaCl Name __________________________ Name __________________________...
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Week3Handout - Name __________________________ Insulin mRNA...

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