LS13 - NPB12 Lecture 13 Vestibulo-Ocular Reflex (VOR)...

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NPB12 Lecture 13
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Vestibulo-Ocular Reflex (VOR)
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Balance: The vestibular apparatus.
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Adriano Moraes on Raindeer Dippin’
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reticular lamina endolymph very high K+ concentration high K+ low K+ equilibrium potential for K+ is +20 mV up here equilibrium potential for K+ is -85 mV down here
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This open voltage-gated Ca++ channels in this part of the membrane. Ca++ Ca++ when these channels open, K+ flows into the cell to bring the membrane potential up here to a more positive value. K+ K+ this causes the synaptic vesicles to fuse with the membrane and release neurotransmitter The neurotransmitter causes ligand-gated Na+ channels to open in the spiral ganglion cells, which then fire action potentials to send the signal to the brain.
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The hair cell does not have action potentials. The spiral ganglion neurons are the first ones to have action potentials There are about 20 spiral ganglion cells for each hair cell.
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Nystagmus and the VOR 1) The vestibular system does ACCELERATION, not velocity 2) Rotating with you eyes closed is the same as being stationary to the vestibular and visual systems. 3) When you stop rotating, the vestibular system signals the change in velocity (it thinks you are rotating in the opposite direction). 4) The VOR then moves your eyes in the opposite direction to compensate.
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LS13 - NPB12 Lecture 13 Vestibulo-Ocular Reflex (VOR)...

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