Lec. 3 (1-12-10) - Psych 9B - PSB 11B Memory 2 Brain...

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Psych 9B -- PSB 11B Memory-2 1 Memory-2 Psych 9B -- PSB 11B 1 Memory 2 Brain structures Memory Storage Blocking
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Psych 9B -- PSB 11B Memory-2 2 Psych 9B -- PSB 11B 2 Memory-2 Consider the following 2 scenarios ± I unlock the door of my office carrying a large box as the phone rings. Later, returning to my office, I realize I do not have my keys and have no idea where they are. ± A 30 year old woman approaches me at a conference and introduces herself as a student who was in a lecture class of mine 8 years before. I have absolutely no recollection of her. Later, when I look her up, I see that I wrote her a recommendation. A. Both (1) and (2) are examples of absent mindedness B. (1) is an example of transience and (2) is an example of absent mindedness C. (1) is an example of absent mindedness and (2) is an example of transience D. Both (1) and (2) are examples of absent transience
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Psych 9B -- PSB 11B Memory-2 3 Psych 9B -- PSB 11B 3 Memory-2 Eye
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Psych 9B -- PSB 11B Memory-2 4 Psych 9B -- PSB 11B 4 Memory-2 Frontal Parietal Occipital Temporal Brain Stem Cerebellum
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Psych 9B -- PSB 11B Memory-2 5 Psych 9B -- PSB 11B 5 Memory-2 Uncovering the Role of the Hippocampus: HM
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Psych 9B -- PSB 11B Memory-2 6 Psych 9B -- PSB 11B 6 Memory-2 Hypotheses about Memory Based HM (& other similar cases) ± Summary of HM’s memory status ² His long-term memory storage and retrieval were unharmed ² His working memory was unaffected ² His deficit involves converting information in working memory into permanent storage ± Inferences about memory systems ² Short-term memories are biologically different from long-term memories ² Long-term memories are stored throughout the brain, or at least not in the hippocampus ² The hippocampus is critical for information to reach long-term storage ² Once a memory is permanent the hippocampus is no longer required to reinstate it This turns out to be wrong!
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Psych 9B -- PSB 11B Memory-2 7 Psych 9B -- PSB 11B 7 Memory-2 ± Which of the following do you think HM would be able to do? i. Learn a new motor skill like riding a bike ii. Exhibit priming in a word-completion task A. Neither (i) or (ii) B. Only (i) C. Only (ii) D. Both (i) and (ii)
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Psych 9B -- PSB 11B Memory-2 8 Psych 9B -- PSB 11B 8 Memory-2 Role of the Hippocampus ± Hippocampus functions bind and connect representations stored in other cortical locations ± Gary Lynch at UCI ² http://www.latimes.com/news/nationworld/nation/la-na- memory-series,0,3457863.special ² His lab developed a procedure to visualize the strengthening of synaptic connections in hippocampal slices (of rats) ± Results ² Strengthening is initiated by a specific pattern of neural stimulation ² Can be disrupted by subsequent stimulation in a 15-20 minute period ² Once stabilized, increased activity at this site calls back the pattern encoded in other parts of cortex
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Psych 9B -- PSB 11B Memory-2 9 Psych 9B -- PSB 11B 9
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This note was uploaded on 11/23/2010 for the course SOCIAL SCI 68100 taught by Professor Wright during the Winter '10 term at UC Irvine.

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Lec. 3 (1-12-10) - Psych 9B - PSB 11B Memory 2 Brain...

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