Bio+97+Worksheet+9 - B io 97 Worksheet 9 1 An autosomal...

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Bio 97 Worksheet 9 1. An autosomal recessive disease, bari-bari, occurs with an incidence of 0.30 among seals. What would be the frequency of heterozygous carrier seals for bari-bari, assuming Hardy- Weinberg equilibrium? A. 0.27 B. 0.36 C. 0.43 D. 0.31 E. 0.50 2. You are investigating the function of protein X. Protein X is known to be 23 kD. You have isolated this protein from yeast and gel electrophoresis has confirmed the size. Somehow, a new batch of yeast suddenly start producing a protein that is 14 kDa instead of 23 kDa. You see a faint band around the 23 kDa marker, so the yeast must be producing protein. What might be happening? Why are we getting a protein that is smaller? 3. A ___________________ will alter the coding sequence of DNA, and consequently, an amino acid will be replaced in the polypeptide. 4. T/F A frameshift mutation will result when a point mutation occurs, and replaces a correct nucleotide with another. 5. Will replacing a single nucleotide be deleterious? What type of point mutation can arise from this?
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