Lecture+notes+10 - Copy - 7 Muscle structure and...

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Lecture Notes Bio 109, Fall 2010, Dr. Catherine Loudon Lecture 10 – 10/18/10 – Muscles 1) Announcements a) Test 1 results posted on Friday, scores ranged from 9/30-30/30 b) Next online quiz (#4) starts today 2) Demonstration of student score calculator (Excel file provided on EEE) 3) Clicker question (any response counts) a) Did you find test 1: i) A. very difficult ii) B. somewhat difficult iii) C. between difficult and easy iv) D. somewhat easy v) E. very easy 4) Muscle cells – the OTHER electrically-excitable cell (Fig. 12-12) a) Action potential propagated along muscle cell – the other electrically-excitable cell type (Fig. 12-12) b) Relationship to AP from somatic motor neuron c) Relationship to development of tension (forces generated within muscle) 5) Muscle types (Fig. 12-1) a) Skeletal, cardiac, smooth b) Number of nuclei c) General appearance of cells (terminology: muscle fiber = 1 muscle cell) d) Striations 6) Antagonistic muscles (Fig. 12-2)
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Unformatted text preview: 7) Muscle structure and composition (Fig. 12-3) a) T-tubules b) Thick and thin filaments (proteins and arrangements) (Fig. 12-5, 12-6) c) [Do not worry about memorizing line and band designations such as A band, Z disk, M line, etc. but do know sarcomere, myofibril, etc.] d) [Do not worry about memorizing names of proteins in thick and thin filaments other than actin and myosin, troponin and tropomysin] 8) Muscle contraction a) Sliding filament theory of contraction (Fig. 12-8) i) Filaments do not change in length ii) Sarcomeres do change in length iii) “Contraction” refers to force generation in a muscle (muscle can be shortening, staying the same length, or lengthening) b) Crossbridge formation and power stroke (Fig. 12-10) c) Role of Ca++ (Fig. 12-10) d) Animation online (http://www.sci.sdsu.edu/movies/actin_myosin_gif.html) e) Initiation by action potential – excitation-contraction coupling (Fig. 12-11)...
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