Lecture+notes+21 - Copy - Lecture Notes Bio 109 Fall 2010...

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Lecture Notes Bio 109, Fall 2010, Dr. Catherine Loudon Lecture 21 – 11/15/10 – Kidneys 1) Kidneys - overview of anatomy and function (Fig. 19-1) a) Regulation of fluid volume (in whole body) b) Regulation of osmolarity c) Regulation of ion balance d) Regulation of pH e) Excretion of wastes (except carbon dioxide – lungs) f) Production/secretion of hormones (e.g. EPO) 2) Blood supply to kidneys (Fig. 19-1) a) Remember 1/5- 1/4 of cardiac output goes to kidneys b) Renal arteries and renal veins 3) Anatomy of renal system a) Kidneys, ureter, bladder, urethra 4) Nephron – functional unit of kidney (Fig. 19-1) a) Location in cortex and medulla b) Association with blood vessels i) Two capillary beds – one at glomerus, and one surrounding loop of Henle (portal system) c) Bowman's capsule i) Site of filtration ii) Surrounds glomerulus iii) Where primary urine (filtrate) is formed d) Proximal tubule e) Descending limb of loop of Henle f) Ascending limb of loop of Henle g) Distal tubule h) Collecting duct 5) Urine formation (Fig. 19-2) a) Filtration b)
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