Lecture+notes+25 - Copy

Lecture+notes+25 - Copy - Lecture Notes Bio 109, Fall 2010,...

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Lecture Notes Bio 109, Fall 2010, Dr. Catherine Loudon Lecture 25 – 11/24/10 – Metabolism and Energy Balance 1) Control of food intake a) Feeding center and satiety center in hypothalamus (Fig. 22-1) i) Satiety center inhibits feeding center ii) Feeding center tonically active b) Leptin secretion by adipose tissue suppresses feeding via neuropeptide Y (Fig. 22-1) c) Many peptides modulate food intake (Table 22-1) you should particularly know: i) Neuropeptide Y ii) Ghrelin iii) Leptin d) Could this be considered homeostatic regulation of body size? 2) Metabolic rate a) Metabolism is the sum of all of the chemical reactions in the body b) Metabolic rate usually refers to energy expenditure i) Measured by heat production (calorimetry) ii) Measured by oxygen consumption rate (indirect calorimetry) c) The ratio of carbon dioxide produced to oxygen consumed is the respiratory quotient RQ i) RQ depends on substrate oxidized – 1.0 for carbohydrates, 0.7 for fat, 0.8 for protein 3) Metabolism
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Lecture+notes+25 - Copy - Lecture Notes Bio 109, Fall 2010,...

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