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Telomeres
Problem: replication ends
Bacteria & other systems have circular chromosomes
Lagging strand problem
Chromosome ends are different
[…..GGGTTC]
telomere (end part of chromosome)
Special substate for adding extra nucleotides at end for telomerase to bind
to
Protective measure
Highly repetitive
Telomerase: reversetranscriptase, encodes the ability to read RNA and turn it
into DNA
Somatic cells: do not reproduce a lot, low telomerase activity
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- Spring '09
- RYTASVILGALYS
- molecular biology, Bacteria, DNA, low telomerase activity, high telomerase activity, repetitive Telomerase
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