{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Review Exam 3 - Regulation of Mean Arterial Pressure...

Info icon This preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Regulation of Mean Arterial Pressure Introduction o MAP = CO x TPR o Two factors influence blood flow to an organ: MAP and organ’s resistance o Any decline in MAP tends to compromise blood flow to all systemic organs o Controlled by medulla oblongata Calculating MAP o Defined as the average arterial pressure during a single cardiac cycle o MAP is usually between 70-110 mmHg If MAP falls below this, organ will not get enough blood flow and will become ischemic o MAP = HR x SV x TPR o ^ in CO or TPR = ^ in MAP MAP regulation o Negative feedback systems incorporating pressure sensors called baroreceptors that sense the arterial pressure o Depolarization triggers increased action potentials o ^ BP = ^ baroreceptors ^ parasympathetic stimulation to decrease HR v sympathetic HR v stroke volume to bring BP back down to normal o v BP = opposite of above Hypertension o Chronic condition that develops slowly over long periods of time o Baroreceptors lose their sensitivity and set “normal” to a higher pressure over time Once this occurs, baroreceptors cannot correct the problem o Can lead to significant organ damage and must be controlled by drugs and exercise Blood Pressure o Eating habits, how much water and blood are in your body, and salt intake can effect BP. Also health of your kidneys and certain hormones o Atherosclerosis (hardening of arteries) – makes arteries prone to injuries and tears Cholesterol and fat are more likely to build up in these tears heart attack or stroke o Stroke 1 st : blood vessels can break, leaking blood into the brain 2 nd : blood clot, blocking blood flow o Heart attack: coronary artery that bring blood to the heart become blocked and the heart cannot get enough oxygen o Enlarged heart: ^ BP makes heart work harder and overtime the heart fails to pump as much blood as the body needs, and fluids back up into the lungs o Waste builds due to kidney damage
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
Blood Introduction o Contains 10 pints of plasma, RBC (erythrocytes), and WBC (leukocytes and platelets) o RBC’s carry oxygen and nutrients, platelets stop bleeding and help heal our wounds and prevent infection, plasma carryies an array of proteins that regulate bleeding and clotting o
Image of page 3

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern