BME 314 Lecture 11 2010

BME 314 Lecture 11 2010 - CardiovascularMechanicsI Krish...

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Cardiovascular Mechanics I Krish Roy, PhD Associate Professor Biomedical Engineering
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Learning Objectives Describe the path of blood flow through the heart Describe the common ailments and current therapies Define a fluid and discuss how it differs from a solid Define a Newtonian fluid (mathematically and in words) Discuss what is a non-Newtonian fluid and describe it characteristics Describe the behavior of blood under flow
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Outline Cardiovascular System and Applications Circulatory System and Blood Flow Common Cardiovascular Therapies Basic Principles of Fluid Mechanics Definition of a Fluid Newton's Law of Viscosity Blood: A Non-Newtonian Fluid
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The Circulatory System: Fluid  Mechanics Average adult has 5 liters of blood, with 80 - 90% in the systemic circulation at any one time. Cardiac Output = Heart Rate x Stroke Volume Each heartbeat = 80 ml (Stroke Volume) How many beats does it take for the average red blood cell to make one complete cycle through the body? 5000 ml / 80 ml = ~62 beats
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Blood flow in the heart: A mechanical Pump
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Cardiovascular Therapies: LVAD A typical type of LVAD will have a tube going into the left ventricle that pulls blood from the ventricle into a pump. The pump then sends blood into the aorta (the large blood vessel leaving the left ventricle). This effectively "bypasses" the weakened ventricle. The pump is placed in the upper part of the abdomen. Another tube attached to the pump is brought out of the wall of the abdomen to the outside of the body and attached to the control system for the pump. LVADs are typically used for weeks to months. A left ventricular assist device is a surgically implanted machine that helps a failing heart pump blood. This instrument is generally used to keep a patient stable until a heart transplant can be performed.
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Valve disorder Mechanical Heart Valves Porcine Heart Valves Valve Replacement
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Vessel Reconstructions Over 600,000 total vascular grafts each year in the U.S. $200 million vascular graft market worldwide. Approximately 500,000 coronary artery bypass operations per year (U.S.). Small vessel reconstruction (<10 mm I.D.): Examples: lower extremity bypass surgeries, coronary artery bypass grafting (CABG) .
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This note was uploaded on 11/29/2010 for the course BME 314 taught by Professor Frey during the Fall '08 term at University of Texas at Austin.

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BME 314 Lecture 11 2010 - CardiovascularMechanicsI Krish...

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