Endovascular stents - E ndovascular stents: A aron B....

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Endovascular stents: Aaron B. Baker, PhD Did undergrad in bioengineering and univ. of Washington PhD between Harvard medical school Stent – small meshed metal tube that is inserted into an occluded artery to restore blood flow Vessel Anatomy – tube or conduit for blood Endothelium –monolayer of cells, has number of functions, controlling thrombosis, controls vasodilation, interface between immune system, controls cells underneath it and regulates their growth Tunica Media – vascular smooth cells Layers of elastin Adventitia – made of collagen and fibers Atherosclerosis – buildup of plaque in the arteries that can block blood flow. Accumulation of lipids, calcium, ECM and proliferating cells Consequences – in coronary arteries it damages the heart muscle $300 billion dollars to treat in US annually (coronary heart disease) ischemia –lack of blood flow to tissue to prevent function infarction – completely blocks blood flow thrombosis – blood clot because attaches to walls of vessells and they bring
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Endovascular stents - E ndovascular stents: A aron B....

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