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What_you_need_to_know_for_the_second_mid

What_you_need_to_know_for_the_second_mid - What you need to...

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What you need to know for the second midterm: You still need to know the structure of the amino acids and their pKas and how the charge varies with pH Protein Secondary structure: You need to know all the structural parameters for alpha helix, beta sheet and beta turns. You need to know how they might fit together. You need to know the Ramachandran plot You need to know why the phi psi angles are limited, generally only. You need to know what kind of residues are common in what structures and which amino acids mess things up Protein Structure and folding: You need to know the definitions of tertiary and quaternary interactions. You need to know what types of interactions stabilize tertiary and quaternary structures. You need to know the driving force of protein folding. You need to understand and describe the folding experiments as related to RNAseA and insulin and be able to generalize those concepts to other systems. You need to know what a chaperone protein is and what it does and how it does it.
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