CNS ANSvF.L12-13_2010FBb - Organization of the Nervous...

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Organization of the Nervous System: CNS, PNS & Introduction to the ANS Physiology Text Figures : Principles of Human Physiology Germann & Stanfield, 2 nd Ed.
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Lecture 12&13 Objectives I. Review synaptic transmission & signal transduction II. Review organization of nervous system III. Peripheral Nervous System IV. Autonomic Nervous System A. Parasympathetic B. Sympathetic Division 1. Anatomy 2. Neurotransmission & Neurochemical metabolism 3. Receptors 4. Physiology 5. Regulation V. Case Study
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Synapse Post-synaptic Cell Pre-synaptic Cell I. Review: Neurotransmission & Signal Transduction
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Electrical Synapses vs. Chemical Synapses • SPEED: no synaptic delay in the electrical synapse • excitatory vs. inhibitory amplification of the signal with chemical synapse Fig 5.1
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Neurotransmission through a Chemical Synapse Post Synaptic Density (PSD) Reuptake transporter
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Review: Signal Transduction at Synapses Germann and Stanfield
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Germann and Stanfield ,
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Central Nervous System : Brain Spinal Cord II. Organization of the Nervous System Input Afferent Output Efferent Peripheral Nervous System Somatic Autonomic Sensory Autonomic Parasympathetic Sympathetic Parasympathetic Sympathetic
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afferent sensory fibers efferent motor fibers (enter CNS via dorsal root) (exit CNS via ventral root) (exit CNS via ventral root) s p i n a l c o r d CNS effector organ effector organ paravertebral or collateral ganglion in tissue  or adrenergic nACh mACh nACh nACh parasympathetic sympathetic S. Sukahrev III. Peripheral Nervous System
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Smooth muscle Gland cells Cardiac muscles Efferent and Afferent Pathways Somatic Sensory Autonomic Skeletal muscle Specialized sensory tissue Viseral Effectors Efferent fibers Send info from CNS to ANS Somatic and Autonomic Afferent fibers ( vagus ) Transmit information from visceral receptors to CNS Important in maintaining homeostasis Sensory and Autonomic
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Preganglionic Cell Postganglionic Cell Synapse within Ganglion
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IV. ANS • Efferent pathways involved in unconscious homeostatic control involves autonomic nervous system (ANS) • Dual Innervation • Parasympathetic and sympathetic activities tend to oppose each other • FUNCTION? • Enteric Nervous System
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Areas of the Brain involved in Autonomic control Germann and Stanfield Figure 12.12 Maintenance of homeostasis Emotions Cerebral cortex Limbic system
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Preganglionic neurons originate in brainstem ( cranial ) or sacral spinal cord Anatomy Long preganglionic neurons to ganglia near effector organ Preganglionic neuron communicates with postganglionic neuron in ganglia Short post ganglionic neurons from ganglia to effector organs IV. A. Parasympathetic Nervous System 1. Anatomy Cranial Nerves Cranial nerve X = vagus nerve Sacral Spinal Nerves Pelvic nerves distinct from somatic spinal nerves
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Germann and Stanfield Figure 12.6 Parasympathetic Nervous System
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Preganglionic neurons originate in thoracolumbar spinal cord General anatomy Short preganglionic neurons to sympathetic chain
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CNS ANSvF.L12-13_2010FBb - Organization of the Nervous...

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