How is DNA damage recognized and converted to cellular responses?G1, S, and G2/MCell cycle arrest
Transmission of the DNA damage response signalPhosphorylation (kinases, phosphatases)Acetylation (e.g. histones)Ubiquitination e.g. cdc25Mobilization and relocalization – recruitment of member proteins in a pathwayto a complex at the site of DNA damageTranscription – e.g. p21
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