Ch43Obj7 - Chapter 43 Objectives 1. Explain what is meant...

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Chapter 43 Objectives 1. Explain what is meant by nonspecific defense, and list the nonspecific lines of defense in the vertebrate body. 2. Explain how the physical barrier of skin is reinforced by chemical defenses. 3. List two types of phagocytic cells derived from white blood cells. 4. Describe the inflammatory response including how it is triggered. 5. Explain how the inflammatory response prevents the spread of infection to surrounding tissue. 6. Describe a plausible mechanism for how interferons can fight viral infections 7. Explain how complement proteins may be activated and how they function in cooperation with other defense mechanisms. 8. Explain how humoral immunity and cell-mediated immunity differ in their defensive activities. 9. Describe where T and B cells migrate after birth, and explain what happens when they are activated by antigens. 10. Explain how a single antigen molecule may stimulate the immune system to produce several different antibodies. 11. Describe the mechanism of clonal selection. 12. Describe the cellular basis for immunological memory. 13. Describe the cellular basis for self-tolerance. 14. Explain how the humoral response is provoked. 15. Diagram and label the structure of an antibody, and explain how this structure allows antibodies to perform the following functions: a. Recognize and bind to antigens b. Assist in destruction and elimination of antigens 16. List the five major classes of antibodies in mammals and distinguish among them. 17. Describe the following effector mechanisms of humoral immunity triggered by the formation of antigen-antibody complexes: a. Neutralization c. Precipitation b. Agglutination d. Activation of complement system. 18. Explain how T-cell receptors recognize "self" and how macrophages, B cells, and some T cells recognize one another in interactions. 19. Design a flow chart describing the sequence of events that follows the interaction between antigen presenting macrophages and helper T cells, including both cell-mediated and humoral immunity. 20. Describe how cytotoxic T cells recognize and kill their targets.
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Ch43Obj7 - Chapter 43 Objectives 1. Explain what is meant...

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