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Oct18 - Biology1020 Lecture15 cytochromes (ironatom)toO2...

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Biology 1020 Lecture 15
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Oxidative phosphorylation Electrons from NADH passed among proteins of the ETC with the help of Coenzyme Q and ________(iron atom) to O 2 ETC generates no ATP directly cytochromes
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Electron transport chain Intermembrane space Intermembrane________ Mitochondrial______ space matrix *will be tested on this folded increases surface area NADH + FADH2 --> NAD + FADH+ oxidized protons and electrons released through complexes H+ move from mito. matrix to the intermembrane space electrons passed down to oxygen oxygen is getting reduced to water
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NADH + H + NAD + + 2e -­૒ + 2H + ____________ Electron transport chain: oxidation of NADH Travel down the ETC To_________ Pumped into _____________ ___________ oxidation oxygen intermembrane space
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H + then moves back across the membrane, passing through channels in______________ Chemiosmosis: use of a H + gradient to drive work [high] [low] ATP synthase
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Chemiosmosis H + gradient across a membrane ʹ high ____________ Movement of protons back into matrix coupled to ATP synthesis by ATP synthase potential energy (high free energy)
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Chemiosmosis H + gradient ʹ a ______________ -­૒ capacity to do work proton-motive force (proton moving force)
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Chemiosmosis _____+ chemiosmosis = oxidative phosphorylation ETC
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ETC-­૒ Chemiosmosis Summary _____ (glycolysis & TCA) and______ (TCA) transfer electrons to ETC ETC complexes located on the mitochondrial inner membrane series of redox reactions NADH FADH(2)
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ETC-­૒Chemiosmosis Summary ____pumped into intermembrane space Electrons delivered to ½____ Proton motive force (intermembrane ƐƉĂĐĞ ї mitochondrial matrix) drives ATP synthesis H+ (protons) O(2)
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ETC Summary Used by ETC Produced by ETC ( + chemiosmosis) NADH FADH(2) NAD+ FAD+ H+ ADP P(I) ATP H+ O(2) H(2)O
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ATP synthesis by cellular respiration Energy flow Organic molecules __________ Proton motive force Produces _______ from organic molecules ATP by substrate phosphorylation NADH most ATP
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ATP synthesis by cellular respiration Most ATP by oxidative phosphorylation in the mitochondrion
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