BioE Test 2 Review - Crossbridge cycle enables power...

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Crossbridge cycle enables power generation/contractility Myosin head group in “relaxed” binding state ATP binding lifts myosin head • ATP hydrolysis initiates “swing” • Phosphate group release allows myosin head (ADP bound) to bind • ADP release locks and pulls myosin neck forward Myosin head group “relaxes” binding... • Unlike kinesin and dynein, more time DETACHED • What happens if there is no more ATP? The length-tension curve governs force generation The length-tension curve predicts a change in force- generating ability with a change in sarcomere length Why would a length-tension curve have this shape? The length-tension curve governs force generation The length-tension curve predicts a change in force- generating ability with a change in sarcomere length Why would a length-tension curve have this shape?
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Contraction force and velocity are hyperbolicall related Muscle function is governed by the force
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