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lec 1b - directional transport of ions Crossing the channel...

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Hydration shell and selectivity of ion K + channels Pore = selectivity „filter‟
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-> selectivity = 1000x! Hydration shell and selectivity of ion K + channels
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O O O O K + O O O O K + K + H H O K + H H O plasma membrane (lipids) Channel „walls‟ „pore” Oxygen atoms from peptide bonds exposed along the aperture of the gate Water molecules of the hydration layer
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