lec 3 - 2-rich blood plasma 2) Cytoplasm rich in...

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Lecture 3: Chemical Foundations IIb Electron Tomography of Membrane-Bound Cellular Organelles Terrence G. Frey, Guy A. Perkins and Mark H. Ellisman Conformational Changes in the Cytochromeb6f Complex Induced by Inhibitor Binding Cecile Breyton
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Building blocks: Amino acids C COO - + H 3 N H R amine acid base + acid = amphoteric link to next aa (NH 3 + ) link to next aa (COO - ) α -carbon Side chain = “R group”
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R: Polar/apolar?
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Hydrophobic amino acids
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Hydrophilic amino acids
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Hydrophilic amino acids: Histidine
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Hydrophilic amino acids Aspartic acid Glutamic acid
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Hydrophilic amino acids
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Hydrophilic amino acids O H : :
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“Special” amino acids
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Cysteine disulfide bridge reduced oxydized
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Cysteine: free or bridged? 3) Sample of plasma treated with mercaptoethanol (CH 3 -CH 2 -SH) 1) O
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Unformatted text preview: 2-rich blood plasma 2) Cytoplasm rich in glutathione (reducing molecule) 1 4 3 2 5 6 A. What family of molecules? On which criteria do you base your answer? D: Which of the atoms/groups 1-6 can establish hydrogen bonds? Which one can make ionic interactions? B: Name the chemical groups corresponding to numbers 2 and 6. C: What are the chemical properties of the R group? Quiz: Building blocks: Sugars carbohydrates-> C + H 2 O = CH 2 O chemical groups: many OH + aldehyde or ketone Building blocks: Sugars large variety of geometries-> high specificity of interactions branching Building blocks: Sugars Building blocks: Sugars modification Building blocks: Sugars Heparin modification...
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This note was uploaded on 12/07/2010 for the course BIO BIOL 200 taught by Professor Frogatto during the Fall '10 term at McGill.

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lec 3 - 2-rich blood plasma 2) Cytoplasm rich in...

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