lec 6 - Regulation of prokaryotic gene expression(pp...

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Regulation of prokaryotic gene expression (pp. 271-276)
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Transcriptional control Usually the major mechanism for controlling production of the protein encoded by a given gene. Transcription of a gene can be repressed (little or no mRNA is synthesized) or activated (up to 1000x or more mRNA is synthesized)
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Unicellular versus multicellular organisms Single-celled organisms Genes are regulated to adjust to changes in the nutritional and physical environment. A cell usually produces only the proteins required for survival and proliferation under the particular environmental conditions it experiences. Multicellular organisms Genes are regulated to ensure coordination during embryonic development and tissue differentiation.
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Operons About half the genes in E. coli are organized into operons. The lac operon encodes 3 enzymes required for the catabolism of lactose. The trp operon encodes 5 enzymes required for the biosynthesis of tryptophan.
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