October21stSupplement - chromosomes not individual genes 1...

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World journal of biological chemistry Forward genetics (mutagenesis screen) in Drosophila Mutagen: ethyl methane sulphonate (EMS) B= Balancer chromosome (a chr with multiple inversions and dominant markers ), M= mutagenized chromosome with a spectrum of mutations Symbols (m and B represent
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Unformatted text preview: chromosomes, not individual genes) 1. EMS mutagenize males are crossed to females with B chr 2. F1 males inherit M chr and are backcrossed to females with B chr 3. F2 males and females carrying the same M chr are crossed with each other 4. 25% of F3 are homozygous for M chr...
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