BIO305_F06_ZHANG_TZFIRA_PracticeExam1 - 1 1. House mouse...

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1 1. House mouse Mus musculus has 2n=40 chromosomes. How many chromosomes exist in a primary spermatocyte and how many in a secondary spermatocyte? a) 20, 20 b) 20, 40 c) 40, 20 d) 40, 40 e) 20, 10 f) 10, 10 g) 40, 10 h) 80, 20 2. In radishes, flower color may be red, purple, or white. No dominance is evident in flower color, and red × white yields all purple flowers. However, radish shape can be either long or oval, and long is dominant to oval. A white oval plant crossed with a plant of unknown genotype and phenotype yields the following offspring: ½ purple long and ½ purple oval The unknown parent a) is homozygous for flower color and radish shape b) had at least one red parent c) had at least one oval parent d) cannot be of long shape e) would produce only one color phenotype if selfed f) would produce three color phenotypes if selfed g) is heterozygous for flower color and radish shape 3. Achondroplasia (dwarfism) is an autosomal dominant human disorder. The pedigree for a family manifesting achondroplasia is shown below. II-2 and II-3 have already had 5 kids, as shown in the pedigree. What is the probability that their next child is a female with achondroplasia? a) 0.5 b) 0.125 c) 0.25 d) 0.0625 e) 1.0 f) 0 g) 0.75 h) 0.2
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2 4. Autosomal gene A determines the coat color of mice. A1 is the wild-type allele that produces the yellow color. A2 is a mutant allele that is dominant to A1, and produces the black color. A2 is also recessive lethal. What is the expected phenotypic ratio among live F1 mice from a cross between two mice that are heterozygous for gene A. a) All black b) All yellow c) 1/3 black, 2/3 yellow d) 3/4 black, 1/4 yellow e) 1/4 black, 3/4 yellow f) 2/3 black, 1/3 yellow g) 1/2 black, 1/2 yellow h) No live F1 mice 5. Which statement about chromosomes and cell divisions in humans is INCORRECT. a) In terms of time, mitosis is usually shorter than interphase. b) For somatic cells, 46 chromosomes can be observed under microscope during the G2 phase. c) Oogenesis is a lengthy process and it starts even before birth. d) A chromosome is called telocentric if the centromere is located at an end of the chromosome. e) P53 regulates cell cycle and is known as a tumor-suppressor gene because tumors may form if it is mutated. f) There is no replication of DNA between meiosis I and II. g) Synapsis of homologous chromosomes does not occur during mitosis. h) During spermatogenesis, spermatids undergo differentiation and become spermatozoa. There is no change in chromosome number during this differentiation process. 6. David and Mary have four children: Mike, John, Dan, and Wendy. It is known that Mike and Wendy have blood type O and John has blood type AB. It is also known that John is red-green colorblind and Dan has normal vision. Which statement is CORRECT. a) Neither of Mary’s parents can be of blood type AB.
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This note was uploaded on 12/12/2010 for the course BIOL 305 taught by Professor Zhang during the Fall '10 term at University of Michigan.

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BIO305_F06_ZHANG_TZFIRA_PracticeExam1 - 1 1. House mouse...

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