Exam 1 -- Winter 2006 -- Blank

Exam 1 -- Winter 2006 -- Blank - Bio 305 Genetics Exam #1...

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Bio 305 Genetics Exam #1 Special Code: 000000 Winter 2006 February 6, 2006 INSTRUCTIONS 1. For your exam to be scored, you MUST use a #2 pencil. The GSIs have extra if you need one. 2. BEFORE BEGINNING THE EXAM, fill out all information sections on the accompanying answer sheet COMPLETELY. a. Read and follow instructions on the form EXACTLY b. Grid in your NAME, STUDENT ID #, and SPECIAL CODE (Top right corner of this page) on the Left-hand side of the answer sheet. c. Be VERY NEAT and careful when filling out the answer form. The scanning machine is very sensitive and stray pencil marks could be interpreted as answers. 3. Each question has only one BEST answer. 4. Assume genes are unlinked, completely penetrant and expressive UNLESS INDICATED OTHERWISE. 5. When you finish, hand your answer sheet to a GSI PERSONALLY. Do not give it to anyone else to hand in. Only one answer sheet will be accepted from each student. 6. The points for each question are indicated. There are 100 points possible. SUGGESTIONS: Work through exam circling answers on paper copy. When you are finished, review your answers. Only then (or with ~15 minutes of exam time left) should you fill in the scantron answer key. Answering questions based on eliminating options is DANGEROUS. Your best bet is to work out each problem completely before looking at answer choices.
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2 Six samples of cells were taken from an actively dividing population at the points during the cell cycle indicated in the diagram on the left. Sample 1 : middle of G 1 Sample 2 : end of G 1 / beginning S phase Sample 3 : end of S / start of G 2 phase Sample 4 : middle of G 2 phase Sample 5 : end of G 2 / start of M phase Sample 6 : start of G 1 phase. Each sample (1-6) was treated with a chemical that causes the chromosomes to condense as they do naturally during prophase. Pictures were taken of chromosomes from each cell sample. 1. (5 pts) Which samples could the picture above of the X and Y chromosomes have come from? (Choose the ONE answer that encompasses all possible stages) (a) 1 2 3 (b) 2 3 4 (c) 3 4 5 (d) 4 5 6 (e) 6 1 2 (f) 1 2 (g) 2 3 (h) 3 4 (i) 4 5 (j) 5 6 Consider a cross between individuals with the following genotypes: AA Bb CC dd Ee Ff gg x aa bb cc dd ee ff gg, 2. (5 pts) What is the probability of a CHILD with the genotype: Aa bb Cc dd Ee ff gg? (a) 1/4 (b) 1/8 (c) 1/32 (d) 1/64 (e) 1/128 (f) 3/4 (g) 3/8 (h) 3/16 (i) 3/64 (j) 3/128 S M G 1 G 2
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3 Fill in (a) for TRUE, (b) for FALSE, and (c) for NEED MORE INFORMATION. (1 pt each) 3. Humans, fruit flies, and worms use different mechanisms to inactivate one X chromosome in females. 4. 65% of individuals homozygous for the BRCA1 mutant allele develop some form of breast cancer. The penetrance of this allele is 65%.
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This note was uploaded on 12/12/2010 for the course BIOL 305 taught by Professor Zhang during the Fall '10 term at University of Michigan.

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Exam 1 -- Winter 2006 -- Blank - Bio 305 Genetics Exam #1...

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