Exam 1 -- Winter 2007 --ANSWERS _do not distribute_

Exam 1 -- Winter 2007 --ANSWERS _do not distribute_ - Bio...

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Bio 305 Genetics Exam #1 Special Code: 000000 Winter 2007 February 5, 2007 INSTRUCTIONS 1. For your exam to be scored, you MUST use a #2 pencil. The GSIs have extra if you need one. 2. BEFORE BEGINNING THE EXAM, fill out all information sections on the accompanying answer sheet COMPLETELY. a. Read and follow instructions on the form EXACTLY b. Grid in your NAME, STUDENT ID #, and SPECIAL CODE . c. Sign your answer sheet AND the first page of your exam. d. Be VERY NEAT. The scanning machine is very sensitive and stray pencil marks could be interpreted as answers. 3. Each question has only one BEST answer. 4. Assume genes are unlinked, completely penetrant and expressive UNLESS INDICATED OTHERWISE by the question. 5. When you finish, hand your answer sheet to a GSI personally. Do not give it to anyone else to hand in. Only one answer sheet will be accepted from each student and you must show your student ID. 6. The points for each question are indicated. There are 105 points possible, but the maximum score you can earn is 100. There are 28 questions. SUGGESTIONS: Work through the exam circling answers on your paper copy. If you get stuck on a question, skip it and come back to it later. If you finish early, review your answers. Only then (or with ~15 minutes of exam time left) should you fill in the scantron answer key. Double check that the answers you filled in match the circles you filled. Answering questions based on eliminating options is dangerous. Your best bet is to work out each problem completely before looking at answer choices. FILL IN AN ANSWER FOR EVERY QUESTION. You have at least a 20% chance of guessing right!
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Bio 305 Genetics Exam #1 Special Code: 000000 Winter 2007 February 5, 2007 Marfan syndrome is an autosomal dominant disease caused by a mutation in collagen formation that affects about 1/60,000 live births. Symptoms of Marfan syndrome include: long fingers and toes, scoliosis, rib and sternum abnormalities, ectopia lentis (a dislocation of the lens into the anterior chamber of the eye), and various cardiovascular abnormalities. Each affected person may express all of the symptoms, or only a few. 1. (5 pts) What genetic phenomenon does Marfan syndrome exhibit? 2. (5 pts) What is the probability that a mother of three children has all boys, given that her oldest child is a boy? Science Daily (May 15, 1998) : A gene that helps keep bad cholesterol at bay -- and may reduce heart disease risk by 50 percent -- has been discovered by researchers reporting in this month’s Arteriosclerosis, Thombosis and Vascular Biology: Journal of the American Heart Association . The MTP gene provides the blueprint for production of a protein that is required to assemble LDL cholesterol. Individuals who carry two copies of a mutant allele of the MTP gene had LDL cholesterol levels 22 percent lower than those who had one copy or no copies of the mutant allele.
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