Presentation5 - Mandible developed from Neckels cartilage...

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Mandible: developed from Neckel’s cartilage, some from endochondral and some from mesenchymal ossification Woven bone also fetal bone: loosely organized bones replaced by lamellar bone and trabecular bone further develops Mesoderm: dentyne, pulp, bones, muscles Endoderm: gut Ectoderm: hair, nails, nervous system Buccopharyngeal membrane: between ectoderm and endoderm, separates mouth and other parts of the gut at 21 weeks Epiphyseal growth plate: formed from metaphysis and diaphysis
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ENDOCHONDRAL OSSIFICATION: as vascular bud penetrates perichondrium to make periosteum with osteoprogenitor cells; matrix starts to calcify; cartilage cells do not receive nutrients so they die. Oldest cells die first, they tend to die faster. When bone breaks, periosteum ruptures. Reparative process begins from 24-48 hours. Area fills with blood. Periosteum will transform itself into cartilage to repair the break. Once normal vasculature is replaced, osteoblasts osteocytes.
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