Aug 30 - Biochem 423 Robert A Orlando Ph.D LIPIDS –...

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Unformatted text preview: Biochem 423 Robert A. Orlando, Ph.D. LIPIDS – NOMENCLATURE 23 | P a g e Biochem 423 Robert A. Orlando, Ph.D. IN BLOOD – SOME FATTY ACIDS ARE BOUND TO ALBUMIN MOST ARE IN THE FORM OF TRIACYLGLYCEROLS…. NUCLEIC ACIDS BASE Purines Adenine Guanine Pyrimidines Thymine Cytosine Uracil 24 | P a g e Biochem 423 Robert A. Orlando, Ph.D. NOMENCLATURE 25 | P a g e Biochem 423 Robert A. Orlando, Ph.D. AMINO ACIDS AMINO ACIDS ARE THE BUILDING BLOCKS FOR PROTEINS SIDE CHAINS DEFINE THE AMINO ACID – KNOW ALL 20 !!! DIFFERENT CLASSES FOR SIDE CHAINS – (EXAMPLES ON NEXT PAGE) NON‐POLAR AROMATIC POLAR – UNCHARGED CHARGED SULFUR CONTAINING 26 | P a g e Biochem 423 Robert A. Orlando, Ph.D. 27 | P a g e Biochem 423 Robert A. Orlando, Ph.D. TITRATION OF AMINO ACIDS – (MULTI‐FUNCTIONAL GROUPS) ISOELECTRIC POINT = (for two ionizable groups) 28 | P a g e Biochem 423 Robert A. Orlando, Ph.D. SIDE‐CHAIN TITRATION – HISTIDINE (THINK ABOUT THE IMPORTANCE – IONIC BOND FORMATION) 1 3 2 pI = isoelectric point = 7.6 pKR + pK2 ISOELECTRIC POINT = (for neutralizing charge) 29 | P a g e ...
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