Oct 6 - Biochem423 RobertA.Orlando,Ph.D AKA. Complex II...

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Biochem 423 Robert A. Orlando, Ph.D. 95 | Page O XIDATIVE P HOSPHORYLATION AKA…. THE E LECTRON T RANSPORT C HAIN AS OPPOSED TO SUBSTRATE LEVEL PHOSPHORYLATION S UMMARY OF O XIDATIVE P HOSPHORYLATION Complex II Succinate dehydrogenase (FADH 2 transfer of electrons)
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Biochem 423 Robert A. Orlando, Ph.D. 96 | Page R EDUCTION P OTENTIALS ‐‐ E NERGY THAT DRIVES ELECTRON TRANSPORT R EMEMBER O HM S L AW V = I X R (V = VOLTS = PUSHING FORCE ) R EDUCTION H ALF R EACTIONS E O ’ (V OLTS ) AT P H 7.0 NAD + + 2 H + + 2 e - NADH + H + 0.32 FAD + 2 H + + 2 e - FADH 2 0.22 CoQ + 2 H + + 2 e - CoQ-H 2 + 0.05 cytochrome b (Fe 3+ ) + 2 e - cyto B (Fe 2+ ) + 0.08 cytochrome c (Fe 3+ ) + 2 e - cyto c (Fe 2+ ) + 0.25 ½ O 2 + 2 H + + 2 e - H 2 O + 0.82 E NERGY HARNESSED TO PUMP PROTONS INTO INNER MITOCHONDRIAL SPACE GENERATE PROTON MOTIVE FORCE
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Biochem 423 Robert A. Orlando, Ph.D. 97 |
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Oct 6 - Biochem423 RobertA.Orlando,Ph.D AKA. Complex II...

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