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Hormones and Cellular Communication

Hormones and Cellular Communication - Cellular...

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Cellular Communication Ligands- molecule that binds to a central metal to produce a coordination complex. The bonding between the metal and ligand generally involves formal donation of one or more of the ligand's electrons. The metal-ligand bonding ranges from covalent to more ionic. Furthermore, the metal- ligand bond order can range from one to three. Receptor- a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. Intracellular Receptors- receptors located inside the cell rather than on its cell membrane. Examples are the class of nuclear receptors located in the cell nucleus and the IP 3 receptor located on the endoplasmic reticulum.
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