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Lecture11 (1)

Lecture11 (1) - BIS101 Lecture11 Transcription Processing...

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BIS101 Lecture 11, 11/2/10 Transcription Processing
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The Central Dogma of Molecular Biology DNA RNA Protein replication replication transcription translation reverse transcription
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LECTURE 11: OUTLINE Transcription: General points about transcription Mechanism of transcription in prokaryotes Initiation Elongation and Termination Eukaryote RNA polymerases Initiation and transcription factors Functional RNAs
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Prokaryotic and eukaryotic transcription Figure 8.11
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RNA DNA 2’ 2’
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Figure 8.2
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A gene is encoded by the 5’-3’ coding  strand. The coding strand has the same sequence as the mRNA! An RNA copy of the coding strand is made by reading the 3’-5’ non-coding or template  strand. template strand = non-coding refers to DNA non-template strand = coding refers to DNA mRNA sequences represent the sense   strand they match the coding  strand (T is replaced by U) Figure 8.6
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Genes can be encoded on both DNA strands Information is always read in the 5’-3’ direction Figure 8.3
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Lecture11 (1) - BIS101 Lecture11 Transcription Processing...

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