F10_L12_chemical_coordination_Compatibility_Mode_

F10_L12_chemical_coordination_Compatibility_Mode_ - Psy 111...

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sy 111 Basic concepts in Biopsychology Psy 111 Basic concepts in Biopsychology ecture 12: Chemical Coordination Lecture 12 Chemical Coordination of Brain & Behavior
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Objectives • Define the different types of chemical communication and introduce hormone action. • Describe the roles of the PVN in coordinating brain and body functions. • Define circadian rhythms and their neural bases in the suprachiasmatic nucleus. • Illustrate the role of diffuse modulatory systems using the example of sleep. • Describe the autonomic nervous system components and pharmacology. Illustrate how the sympathetic and parasympathetic work in opposition or in conjunction to each other. • Define endocrine glands and their locations in the body and brain. • Compare peptide hormones and steroids to neurotransmitters. • Describe the effects of steroids on cells and brains structures. escribe the hypothalamus ituitary relation Compare the anterior Describe the hypothalamus-pituitary relation. Compare the anterior and posterior portions of the pituitary. • Describe the HPA and HPG axes.
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Types of Chemical Communication Neurotransmission-point to point lso, have the ocal eurons; process iffuse Modulatory ordination Also, have the Local neurons; process parallel paths of information. Diffuse Modulatory-coordination throughout brain Autonomic-parallel networks throughout body Endocrine-blood stream throughout body to all cells
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Overview Diffuse Modulatory Systems – Circadian Rhythms: Hypothalamus & Modulatory Systems • Autonomic Nervous System • Endocrine System – Hormones – Hypothalamus, pituitary, & endocrine regulation
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Diffuse Modulatory Systems Discrete nuclei send vast projections throughout the brain serving to coordinate brain function. t i i ii l di tl Neurotransmission is reciprocal (indirectly; i.e. the nuclei which send diffuse projections are under control of other brain regions).
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Acetylcholine Basal forebrain cells have very diffuse projections (coordinate ther brain areas): other brain areas): Basal forebrain -learning/memory Midbrain -regulate sensory systems
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Dopamine SN – motor (e.g. innervates striatum) VTA – motivation (innervates limbic ructures) structures)
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Dopamine – target of drugs of abuse TA VTA
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Norepinephrine rousal (i e Diverse) functions Arousal (i.e. Diverse) functions -attention, learning, sleep/wake, anxiety, etc
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Serotonin Many nuclei in Raphe “Arousal” functions -mood, sleep/wake
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Serotonin & antidepressants New antidepressants block 5HT transporter “SSRI” -inc only 5HT Old antidepressants inhibit MAO (“MAOI”) -inc 5HT , NE, DA.
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Overview • Diffuse Modulatory Systems Circadian Rhythms: Hypothalamus & Modulatory systems • Autonomic Nervous System • Endocrine System – Hormones – Hypothalamus, pituitary, & endocrine regulation
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