F10_L14_learning_memory_II

F10_L14_learning_memory_II - Psy 111 Basic concepts in...

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Psy 111 Basic concepts in Biopsychology Lecture 13-14: Neural Bases of Learning/Memory
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Limbic: Lobe, Circuit, & System •In the 1950’s, MacLean revised Papez’s work leading to a more encompassing group of structures in the forebrain cortex (telencephalon) and subcortex (diencephalon) involved in emotion which he termed the “limbic system ”. Although there is continuous debate over whether this constitutes t oug t e e s co t uous debate o e et e t s co st tutes a system equivalent to sensory or motor systems and which structures should be included… ut these structures do interact to mediate the psychological But these structures do interact to mediate the psychological processes of motivation, emotion, and (several forms of) memory.
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ature of Learning and Memory Nature of Learning and Memory he basic property of learning/memory is the The basic property of learning/memory is the utilization of information for a later time point . •T h i s r e quires that information be not only qy encoded by sensory/perceptual systems but that the information is somehow stored (i.e. maintained with the brain) and retrieved at the later time point. • The physiological substrate of memory is referred to as the “engram” and the precise asis of this is just starting to be understood basis of this is just starting to be understood.
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Conceptualized Storage of Information
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Objectives Discuss the types of memory tasks that are sensitive to hippocampal damage and the type of processes believed to occur in this structure. Describe the circuitry of the hippocampus (including cortical input and alamic output). thalamic output). Illustrate the bi-directional plasticity observed in at the CA3 to CA1 synapse (i.e. LTP and LTD) and the specific roles of NMDA and AMPA receptors in these changes. Discuss the AMPA receptor trafficking ypothesis of synaptic plasticity. hypothesis of synaptic plasticity. Describe the role of the dorsal striatum and cerebellum in motor learning. Discuss the connectivity of the prefrontal cortex (PFC) with the limbic system and its roles in learning and memory.
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verview Overview onceptual issues of learning/memory Conceptual issues of learning/memory. • Simple systems learning & neuroplasticity. • Declarative learning in medial temporal lobe & hippocampus • Procedural memory in striatum & cerebellum. • Role of prefrontal cortex
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Types of Learning & Memory Memory are the system(s) in the brain the acquires, stores (consolidation), and retrieves information. here are multiple types of memory which seem to have somewhat There are multiple types of memory which seem to have somewhat independent neural substrates.
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H.M. Epileptic patient with foci in medial temporal lobe Epilepsy cured by removal of foci.
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F10_L14_learning_memory_II - Psy 111 Basic concepts in...

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