Lecture18 - BCH 227 FALL 2010 LECTURE 18: GLYCOLYSIS 12 OCT...

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1 Glycolysis BIOCHEM 227 FALL 2010 Lecture 18 Wednesday, October 13, 2010 TODAY • Continued: redox • Phosphate-based energy carriers • Glycolysis BCH 227 FALL 2010 LECTURE 18: GLYCOLYSIS 12 OCT 2010
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2 Example: Addition of Oxygen Example: Double Bond BCH 227 FALL 2010 LECTURE 18: GLYCOLYSIS 12 OCT 2010
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3 Counting Electrons Counting Electrons BCH 227 FALL 2010 LECTURE 18: GLYCOLYSIS 12 OCT 2010
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4 Revisiting Those First Examples •Combu s t ion –of wood –of methane • Biological – acetaldehyde/ethanol
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5 Phosphate-Based Energy Carriers • Some phosphate compounds have a very negative Δ G for hydrolysis of a phosphate under cellular conditions –ATP – GTP, etc. – phosphoenolpyruvate – phosphocreatine – 1,3-bisphosphoglycerate Phosphate-Based Energy Carriers BCH 227 FALL 2010 LECTURE 18: GLYCOLYSIS 12 OCT 2010
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6 ATP • The main temporary energy store in cells • The main carrier for shuttling energy in cells •V e ry un s t ab l e thermodynamically , but reasonably stable kinetically – Lots of energy available, but need an enzyme to release it (by the way, also a nucleotide) ATP High-energy phosphate bond
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7 ATP BCH 227 FALL 2010 LECTURE 18: GLYCOLYSIS 12 OCT 2010
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This note was uploaded on 12/19/2010 for the course BIOCHEM 227 taught by Professor Coggins during the Fall '10 term at Duke.

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Lecture18 - BCH 227 FALL 2010 LECTURE 18: GLYCOLYSIS 12 OCT...

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