Lecture20 - BCH 227 FALL 2010 LECTURE 20 FERMENTATION...

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1 Fermentation The Production of Beer BIOCHEM 227 FALL 2010 Lecture 20 Monday, October 18, 2010 TODAY Continued: pentose phosphate pathway • Fermentation Biochemistry of beer BCH 227 FALL 2010 LECTURE 20: FERMENTATION; PRODUCTION OF BEER 18 OCT 2010
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2 Pentose Phosphate Pathway Pentose Phosphate Pathway Nonoxidative phase – When only the NADPH is needed, this recycles ribose to glucose-6-phosphate – Direct conversion would require energy/reduction No point in doing that – Instead, six pentoses are converted to five hexoses No energy input Catalyzed by transketolase and transaldolase – Same reactions are reversed in the dark reactions of photosynthesis BCH 227 FALL 2010 LECTURE 20: FERMENTATION; PRODUCTION OF BEER 18 OCT 2010
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3 Nonoxidative Pathway Nonoxidative Pathway BCH 227 FALL 2010 LECTURE 20: FERMENTATION; PRODUCTION OF BEER 18 OCT 2010
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4 Transaldolase Transketolase BCH 227 FALL 2010 LECTURE 20: FERMENTATION; PRODUCTION OF BEER 18 OCT 2010
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5 Pentose Phosphate Pathway Fermentation BCH 227 FALL 2010 LECTURE 20: FERMENTATION; PRODUCTION OF BEER 18 OCT 2010
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6 Anaerobic Metabolism & NADH In anaerobic metabolism, there is no electron acceptor, so oxidation is not possible NADH accumulates, and the cell runs out of NAD + Fermentation Process of recycling NADH to NAD + (oxidation of NADH) A carbon compound is reduced Nothing useful is done with the electrons A small amount of energy is obtained from glucose by glycolysis BCH 227 FALL 2010 LECTURE 20: FERMENTATION; PRODUCTION OF BEER 18 OCT 2010
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