Lecture25 - BCH 227 FALL 2010 LECTURE 25: REGULATION OF...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Regulation of Glucose Oxidation BIOCHEM 227 FALL 2010 Lecture 25 Friday, October 29, 2010 Regulation • Metabolism is carefully regulated – must maintain homeostasis • constant supply of precursors • constant supply of energy • avoid waste of energy/material BCH 227 FALL 2010 LECTURE 25: REGULATION OF GLUCOSE OXIDATION 29 OCT 2010
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 Steady-State • Cell is in steady-state – metabolite concentrations are constant • allosteric regulators adjust flux in pathways –thermodynam ics • some reactions are in equilibrium • other reactions are not • changing concentrations causes flux (Le Châtelier) – kinetics • regulators affect enzyme activity • increase/decrease flux Steady-State Example: ATP • [ATP]/[AMP] = constant – affects •amoun t o f ATP •amoun t o f
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 12/19/2010 for the course BIOCHEM 227 taught by Professor Coggins during the Fall '10 term at Duke.

Page1 / 11

Lecture25 - BCH 227 FALL 2010 LECTURE 25: REGULATION OF...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online