Lecture33 - BCH 227 FALL 2010 LECTURE 33: FATTY ACID...

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1 Fatty Acid Synthesis Glycogen Metabolism BIOCHEM 227 FALL 2010 Lecture 33 Friday, November 19, 2010 Course Announcement CS 196.1: Algorithms in Drug Design Bruce Donald, Computer Science and Biochemistry • A course on how computers can be (and are) used in the process of drug discovery. Combining biochemical and structural data with principles from physics, one can design molecules that will be effective pharmaceuticals. This course presents the sophisticated algorithms that make this possible. • Prereq: Must know how to program. Some familiarity with algorithms would be helpful. BCH 227 FALL 2010 LECTURE 33: FATTY ACID SYNTHESIS; GLYCOGEN METABOLISM 18 NOV 2010
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2 TODAY • Continuation: Fatty Acid Synthesis – FAS complex – elongation – desaturation – PKS complexes • Glycogen Fatty Acid Synthase • Giant complex • ACP = acyl carrier protein – carries growing fatty acid on the complex – moves fatty acid between enzymes in complex •S ix en zym e s – four for the steps
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3 Acyl Carrier Protein Fatty Acid Synthesis BCH 227 FALL 2010 LECTURE 33: FATTY ACID SYNTHESIS; GLYCOGEN METABOLISM 18 NOV 2010
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4 BCH 227 FALL 2010 LECTURE 33: FATTY ACID SYNTHESIS; GLYCOGEN METABOLISM 18 NOV 2010
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5 Fatty Acid Synthase BCH 227 FALL 2010 LECTURE 33: FATTY ACID SYNTHESIS; GLYCOGEN METABOLISM 18 NOV 2010
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6 BCH 227 FALL 2010 LECTURE 33: FATTY ACID SYNTHESIS; GLYCOGEN METABOLISM 18 NOV 2010
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This note was uploaded on 12/19/2010 for the course BIOCHEM 227 taught by Professor Coggins during the Fall '10 term at Duke.

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Lecture33 - BCH 227 FALL 2010 LECTURE 33: FATTY ACID...

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