HW4exno2 - Aricept, vitamin E, and placebo versions of...

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Homework Assignment 4 example Article: Vitamin E fails to stop progress of Alzheimer’s April 19th, 2005 by Nicolas Bakalar Source: New York Times NOTE: you cannot use this article for the homework assignment I. Goal: To determine whether taking Vitamin E slows progression of Alzheimer’s II. Model being tested: Model 1: Vitamin E slows progression of Alzheimer’s disease Model 2: Vitamin E does not slow progression of Alzheimer’s disease III. Design Features: 1. Experiment: a) what done: participants were assigned to receive Vitamin E or a placebo b) for what purpose: to determine the effects of Vitamin E on the rate of pogression of Alzheimer’s disease (you can answer this all in 1 simple sentence, just address both parts a and b) 2. Controls: a) was the experiment controlled? Yes b) Treatment group = people who took Vitamin E c) Control group = people who took a placebo A. Explicit protocol 1. relevant: yes 2. status: present 3. quotes: “patients were randomly assigned to groups receiving a drug
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Unformatted text preview: Aricept, vitamin E, and placebo versions of those substances.” B. Replication 1. relevant: yes 2. status: present 3. quotes: “researchers studied 769 patients” C. Standards 1. relevant: yes 2. status: present 3. quotes: “At the end of one year, significant differences appeared: 38 patients in the placebo group and 33 in the vitamin E group had Alzheimer’s, compared with only 16 in the Aricept group. But among the 214 patients who progressed to Alzheimer’s over the entire 3 year course of the study, there was no significant difference among the three test groups.” D. Randomization 1. relevant: yes 2. status: present 3. quotes: “patients were randomly assigned to groups receiving. .” E. Blind 1. relevant: yes 2. status: present 3. quotes: “patients were randomly assigned to groups receiving a drug Aricept, vitamin E, and placebo versions of those substances.” NOTE: Placebo will be accepted as evidence that study was done blindly....
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This note was uploaded on 12/20/2010 for the course BIO 301D taught by Professor Bull during the Spring '08 term at University of Texas at Austin.

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HW4exno2 - Aricept, vitamin E, and placebo versions of...

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