Practice Gene Mapping Problems

Practice Gene Mapping Problems - Gene Mapping - an Example...

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Gene Mapping - an Example Construct a genetic map using the following data: A line of drosophila has been constructed with three recessive mutations: sc = loss of thorax bristles ("scute") ec = roughened eye surface ("echinus") vg = vestigial wings The dominant, wild-type version of each allele could be written as vg+ or ec+, but we will write them just as "+" for simplicity. P: we cross homozygous recessive flies (sc ec vg / sc ec vg) with homozygous dominant (wild-type) flies (+++ / +++). F1: All of the flies produced by the parental cross have the dominant (wild-type) phenotype. Genetically, these flies are: (sc ec vg / +++) F2: we produce an F2 generation by mating the F1 flies with homozygous recessive flies (sc ec vg / sc ec vg) . This cross produces an F2 generation with 6 different phenotypes: sc ec vg 417 (parental combination of alleles) + + + 430 (parental combination of alleles) sc + + 25 + ec vg 29 sc ec + 44 + + vg 37 sc + vg 4 + ec + 5 total flies in F2: 991 From this genetic data determine the recombination frequencies between each pair of
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Practice Gene Mapping Problems - Gene Mapping - an Example...

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