CH 5 - CH.5.GroundRulesofMetabolism Objectives: KeyTerms:

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CH. 5. Ground Rules of Metabolism    Objectives:   Key Terms : 1.     Understand the properties and nature of energy flow in living organisms. 2.     Recognize the significance of the one-way flow of energy. 3.     Understand the nature of energy at the molecular level, ATP, and enzymes.  4.     Know what metabolism is and the control functions for metabolic reactions.  5.     Know the mechanisms by which substances are moved across membranes against a  concentration         gradient.  6.     Provide an example of a metabolic pathway and explain what kinds of substances regulate  activity of          the pathway. 7.     Tell exactly what enzymes do and how they do it. energy first law of thermodynamics entropy second law of thermodynamics endergonic aerobic respiration exergonic ATP phosphorylation ATP/ADP cycle reactants intermediates end products energy carriers enzymes cofactors transport proteins chemical equilibrium oxidation-reduction reaction “redox” reactions electron transfer chains metabolic pathways biosynthetic (anabolic) degradative (catabolic) activation energy substrates
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active sites rearrangements condensation transition state induced-fit model coenzymes antioxidants free radicals NAD + , NADP + allosteric site feedback inhibition selective permeability concentration gradient diffusion electric gradient pressure gradient passive transport facilitated diffusion active transport exocytosis endocytosis calcium pump sodium-potassium pump bulk flow osmosis solutes tonicity hypotonic solution hypertonic solution isotonic solution hydrostatic pressure turgor osmotic pressure receptor-mediated endocytosis phagocytosis bulk-phase endocytosis                                    Lecture Outline: Impacts, Issues: Alcohol, Enzymes, and Your Liver A.    The liver is your body’s detoxification center. 1.     Polar ethanol molecules move quickly from your stomach to your bloodstream. 2.     Beverage alcohol is degraded by the enzyme catalase in the liver. 3.     Bing drinking by college age students damages the liver, and is a strong factor in increased  accident rates, assaults, date rape, and unprotected sex.
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4.     Bing drinking can even result in heart failure. B.    Your liver is the largest gland in your body and performs many functions relative to food  utilization, including synthesis of plasma proteins. 5.1      Energy and the World of Life  A.    Energy Disperses 1.     Energy is the capacity to do work. a.     The 
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This note was uploaded on 12/21/2010 for the course BIO 03 taught by Professor Garcia during the Fall '08 term at Los Angeles City College.

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CH 5 - CH.5.GroundRulesofMetabolism Objectives: KeyTerms:

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