CH 11 - CH.11.ChromosomesandHumanInheritance Objectives:...

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CH. 11. C hromosomes and Human Inheritance    Objectives :       Key Terms : 1.     Distinguish between autosomes and sex chromosomes. Understand how sex is determined. 2.     Distinguish  autosomal recessive inheritance  from  sex-linked recessive inheritance.  Give  examples of each of the above types of inheritance. 3.     Understand how changes in chromosome structure and number can affect the outward  appearance of organisms. 4.     Describe how an understanding of chromosomes helps to account for events that compose  mitosis and meiosis. 5.     Name some ordinary and extraordinary chromosomal events that can create new  phenotypes (outward appearances). 6.     Explain how changes in chromosomal number can occur and present an example of such a  change. 7.     Explain how modern methods of genetic screening are used as diagnostic procedures and  how they can minimize potentially tragic events. gene pairs of homologous chromosomes alleles wild-type mutant crossing over genetic recombination X chromosome Y chromosome sex chromosomes autosomes SRY  gene testosterone nonsexual traits spectral karyotyping linkage groups pedigree genetic abnormality genetic disorder syndrome disease
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genetic disease autosomal dominant inheritance achondroplasia Huntington disease expansion mutation autosomal recessive inheritance galactosemia X-linked inheritance color blindness hemophilia A Hutchinson-Gilford progeria syndrome duplication inversion deletion cri-du-chat translocation aneuploidy polyploidy nondisjunction trisomy 21 Down syndrome Turner syndrome XXX syndrome Klinefelter syndrome XYY condition abortion genetic screening phenylketonuria, PKU prenatal diagnosis embryo fetus amniocentesis chorionic villi sampling fetoscopy genetic counseling preimplantation diagnosis in vitro fertilization     Lecture Outline :                   Impacts, Issues: Strange Genes, Tortured Minds            A.   Neurobiological disorders (NBDs) include schizophrenia, depression, bipolar disorder, and  autism.                   1.   A higher percentage of geniuses have NBDs compared to the general population.
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                  2.   Highly creative people have more personality traits in common with the mentally ill  than with normal, less creative people.            B.   Changes in genes contribute to the abnormal biochemistry in NBDs.          11.1.       Human Chromosomes         A.    Autosomes and Sex Chromosomes 1.     Most animals have a diploid chromosome number and pairs of homologous chromosomes. 2.     Sex chromosomes determine gender.
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This note was uploaded on 12/21/2010 for the course BIO 03 taught by Professor Garcia during the Fall '08 term at Los Angeles City College.

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CH 11 - CH.11.ChromosomesandHumanInheritance Objectives:...

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